Exjade 500mg Tablet (Generic Equivalent)

Generic Exjade 500mg Tablet contains Deferasirox as its active ingredient. Deferasirox is an active chelator selective to iron as the iron ion Fe3+ has a high affinity to binding at a 2:1 ratio. It is a medication used to lower iron levels in the blood. Two molecules of Deferasirox bind with one atom of iron, forming a stable complex molecule that does not harm the body and passes through the kidneys and out through the individual's urine. It works for treating iron toxicity.

The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional. It should not be understood to indicate that the use of this medicine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Exjade is not recommended for women who are pregnant as it may harm the baby. It is usually not prescribed unless the benefits outweigh the risks. It should also not be used while breastfeeding.

It is essential to stay well hydrated while taking this medication as the mechanism of action of this medication may put extra pressure on your kidneys, aggravating them and worsening any condition if you already have them.

Regular blood tests, urine tests, and hearing tests are essential when using this medication to monitor kidney function, rule out severe side effects, and ensure safe usage.

This medication may interact with other drugs and harm your body. It is important to inform your doctor about any medications you are currently taking, whether they are prescription, over-the-counter, or have been ingested.

Some of the most common side effects that may occur with the use of this medication are:

• Diarrhea

• Nausea and vomiting

• Abdominal pain and discomfort

• Indigestion

• Loss of appetite

• Skin rashes or itching

• Fatigue and weakness

• Headache

• Mild hair thinning

• Elevated liver enzymes

Some serious side effects of this medication are:

• Hepatotoxicity: Jaundice, Dark urine, severe abdominal pain in the right upper quadrant, unexplained fatigue and weakness

• Nephrotoxicity: Creased urine output, swelling in legs and ankles, fatigue or weakness

• Bleeding in the GI tract: Vomit that looks like coffee grounds, bloody/tarry stools, severe abdominal pain

• Hearing loss or tinnitus

• Pancreatitis: Severe upper abdominal pain, nausea and vomiting, fever, jaundice

• Bone marrow suppression, which leads to low blood cell count: Frequent infections, easy bruising and bleeding, fatigue or weakness

If you experience any mild side effects, it is usually not a cause for concern as they resolve by themselves once you stop taking the medicine; however, if they persist, you must follow up with your doctor for the same.  If you happen to encounter any serious side effects, seek medical attention immediately.

• This medication is to be taken orally.

• Do not take this medication without a prescription. Do not share this medication with anyone with the same or similar symptoms.

• Keep it at room temperature, away from children.